The STRAW+10 staging system for the menopausal transition defines late menopausal transition (Stage -1) based on which specific criterion?

• A Elevated FSH >25 IU/L on day 2–5 of any cycle
• B Cycle length variability >7 days from normal cycle length on at least two consecutive cycles
• C Final menstrual period confirmed 12 months retrospectively
• D One amenorrhoeic episode of ≥60 days (and elevated FSH >25 IU/L) within the past year ✓

Explanation

The STRAW+10 (Stages of Reproductive Aging Workshop) framework stages reproductive aging in 10 stages. The Late Menopausal Transition (Stage -1) is characterised by ≥1 skipped menstrual cycle with an amenorrhoea interval of ≥60 days, and FSH levels are usually >25 IU/L (sometimes variably elevated). This stage lasts ~1–3 years. The Final Menstrual Period (FMP) is only definable retrospectively after 12 months of amenorrhoea (Stage +1a = early postmenopause). Stage -2 (early transition) = cycle length variability >7 days. Stage +2 = late postmenopause.

Reference: Shaw's Textbook of Gynaecology, 17th ed.

High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP

Written and medically reviewed by the StethoPrep medical team.