Obstetrics & Gynaecology · Labour Abnormalities, Induction and Operative Delivery

The ARRIVE trial (2018) assessed elective induction at 39 weeks in low-risk nulliparous women. Its main finding was:

  • A Induction at 39 weeks reduced caesarean delivery rate and perinatal mortality without increasing morbidity
  • B Induction at 39 weeks significantly increased caesarean section rate
  • C Induction at 39 weeks increased NICU admissions
  • D No difference in caesarean rates but increased neonatal jaundice
Correct answer: A. Induction at 39 weeks reduced caesarean delivery rate and perinatal mortality without increasing morbidity

Explanation

The ARRIVE trial (NEJM 2018) enrolled low-risk nulliparous women and demonstrated that elective induction at 39 weeks actually reduced the caesarean delivery rate (18.6% vs 22.2%) and perinatal mortality/morbidity was not increased. This counter-intuitive finding challenged the prior assumption that induction of labour always increases caesarean risk, and has shifted practice toward offering elective induction at 39 weeks.

Reference: Williams Obstetrics, 26th ed.

High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP

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