Regarding the WHO classification of anovulation, a woman with low gonadotropins, low estradiol, and a normal prolactin level is classified into which group?

• A WHO Group IV (hyperprolactinemic anovulation)
• B WHO Group II (normogonadotropic normoestrogenic anovulation)
• C WHO Group III (hypergonadotropic hypoestrogenic anovulation)
• D WHO Group I (hypogonadotropic hypogonadal anovulation) ✓

Explanation

WHO Group I is defined by low FSH, low estradiol, and normal prolactin, typically due to hypothalamic suppression (functional, Kallmann syndrome, or idiopathic). WHO Group II has normal FSH and estradiol (includes most PCOS cases). WHO Group III has elevated FSH with low estradiol (ovarian failure). There is no WHO Group IV in the standard three-group classification.

Reference: TEAM Spencer, Clinical Gynecology, or Fritz MA, Clinical Reproductive Medicine, Standard textbook ed.

High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP

Written and medically reviewed by the StethoPrep medical team.