The 2023 revised international PCOS diagnostic criteria (International evidence-based PCOS guideline) now requires which of the following for diagnosis in adults?
- A Mandatory hyperandrogenism plus one other Rotterdam criterion
- B At least 2 of 3 Rotterdam criteria: oligo-anovulation, hyperandrogenism, or polycystic ovarian morphology (PCOM) ✓
- C LH:FSH ratio > 2:1 as a prerequisite
- D AMH level above 5 ng/mL as the primary diagnostic test
Correct answer: B. At least 2 of 3 Rotterdam criteria: oligo-anovulation, hyperandrogenism, or polycystic ovarian morphology (PCOM)
Explanation
The 2023 International PCOS Guideline retained the Rotterdam 2003 criteria requiring ≥ 2 of 3 features (oligo/anovulation, clinical or biochemical hyperandrogenism, and PCOM) after exclusion of other causes, while updating PCOM thresholds (follicle count ≥ 20 per ovary on modern high-frequency ultrasound, or ovarian volume ≥ 10 mL). Hyperandrogenism alone is not mandatory. LH:FSH ratio is neither sensitive nor specific enough, and AMH is an adjunct, not a standalone diagnostic criterion.
Reference: Shaw's Textbook of Gynaecology, 17th ed.
High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP
Written and medically reviewed by the StethoPrep medical team.