Obstetrics & Gynaecology · Infertility, PCOS, and Contraception

According to the Rotterdam 2003 consensus criteria, which TWO of the following three features must be present for a diagnosis of PCOS?

  • A Oligoovulation/anovulation, hyperandrogenism, and polycystic ovarian morphology — all three required
  • B Polycystic ovarian morphology alone is diagnostic
  • C Any two of: oligo/anovulation, clinical/biochemical hyperandrogenism, polycystic ovarian morphology on ultrasound
  • D Elevated LH:FSH ratio > 2:1 is mandatory for diagnosis
Correct answer: C. Any two of: oligo/anovulation, clinical/biochemical hyperandrogenism, polycystic ovarian morphology on ultrasound

Explanation

The Rotterdam 2003 consensus requires any two of three criteria: (1) oligoovulation or anovulation, (2) clinical or biochemical signs of hyperandrogenism, and (3) polycystic ovarian morphology on ultrasound (≥ 12 follicles 2–9 mm or ovarian volume > 10 mL), after exclusion of other causes. All three are not required; polycystic morphology alone is insufficient; LH:FSH ratio is not part of the formal diagnostic criteria.

Reference: Shaw's Textbook of Gynaecology, 17th ed.

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