Which histological pattern of degeneration is the MOST common form seen in uterine leiomyomas?

• A Fatty (lipoleiomyomatous) change
• B Cystic degeneration
• C Myxoid degeneration
• D Hyaline degeneration ✓

Explanation

Hyaline degeneration accounts for over 60% of all degenerative changes in fibroids and results from vascular compromise producing homogeneous eosinophilic glassy stroma. Cystic degeneration develops when hyalinised areas liquefy, and fatty change is typically postmenopausal. Myxoid degeneration is rare but important because it raises concern for myxoid leiomyosarcoma. Red degeneration is dramatic clinically but far less frequent than hyaline change.

Reference: Shaw's Textbook of Gynaecology, 17th ed.

High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP

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