Obstetrics & Gynaecology · Endometriosis, Adenomyosis and Fibroids

Regarding adenomyosis, which MRI feature is MOST specific for diagnosis?

  • A Uterine size >14 cm on T2-weighted MRI
  • B Junctional zone thickness ≥12 mm on T2-weighted MRI
  • C Hyperintense foci within the myometrium on T2-weighted MRI
  • D Diffuse uterine enlargement with globular configuration
Correct answer: B. Junctional zone thickness ≥12 mm on T2-weighted MRI

Explanation

Junctional zone (JZ) thickness on T2-weighted MRI is the most specific and sensitive marker for adenomyosis. A JZ thickness ≥12 mm (or JZ max–min ratio >40%) has the highest diagnostic accuracy. The JZ represents the inner myometrial layer (hypointense on T2). Hyperintense foci within low-signal myometrium also suggest ectopic glands/hemorrhage, but JZ thickening ≥12 mm is the established diagnostic criterion. Uterine enlargement and globular configuration are supportive but nonspecific.

Reference: Shaw's Textbook of Gynaecology, 17th ed.

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