Obstetrics & Gynaecology · Endometrial Carcinoma

A 55-year-old woman with FIGO Stage IA grade 1 endometrioid endometrial carcinoma undergoes total laparoscopic hysterectomy with bilateral salpingo-oophorectomy. Intraoperatively, the uterus is opened and tumor is found to invade 40% of myometrial thickness. No LVSI is present. Sentinel lymph node mapping was not performed. What is the most appropriate next step in management?

  • A Proceed with full pelvic and para-aortic lymphadenectomy
  • B No further surgery; surveillance is appropriate
  • C Adjuvant vaginal cuff brachytherapy only
  • D Adjuvant external beam pelvic radiotherapy
Correct answer: B. No further surgery; surveillance is appropriate

Explanation

Stage IA grade 1 with less than 50% myometrial invasion and no LVSI carries a lymph node metastasis risk of less than 1%. The PORTEC and GOG-99 trials demonstrated that low-risk and low-intermediate-risk patients do not benefit from lymphadenectomy or adjuvant radiation. Sentinel lymph node mapping is optional but not mandatory in this low-risk scenario. Full lymphadenectomy does not improve survival and adds morbidity. Surveillance with regular follow-up is the standard of care.

Reference: Bailey and Love's Short Practice of Surgery, 28th ed.

High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP

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