Endometrioid adenocarcinoma of the endometrium is graded by the proportion of non-squamous solid growth pattern. A tumour shows 30 percent non-squamous solid areas. What is its FIGO grade?

• A Grade 2 ✓
• B Grade 1
• C Grade 3
• D Grade cannot be assigned until myometrial invasion is assessed

Explanation

FIGO grades endometrioid carcinoma on architectural pattern: grade 1 has 5 percent or less, grade 2 has 6 to 50 percent, and grade 3 has more than 50 percent non-squamous solid areas. Thirty percent therefore makes this grade 2. Squamous differentiation is ignored because it carries no adverse significance. Notable nuclear atypia raising an architecturally grade 1 or 2 tumour by one grade is a modifier, not the primary criterion.

Reference: Berek and Novak's Gynecology, 16th ed.

High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP

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