Obstetrics & Gynaecology · Endometrial Carcinoma

Which is the most common histological subtype of endometrial carcinoma?

  • A Endometrioid adenocarcinoma
  • B Clear cell carcinoma
  • C Uterine serous carcinoma
  • D Mixed Mullerian tumour
Correct answer: A. Endometrioid adenocarcinoma

Explanation

Endometrioid adenocarcinoma accounts for approximately 80 to 85 percent of endometrial carcinomas and is typically oestrogen dependent, arising against a background of hyperplasia. Uterine serous carcinoma contributes roughly 10 percent and clear cell about 4 percent, both belonging to the biologically aggressive Type II category. The key fact that eliminates the distractors is that serous and clear cell types, although high yield, together form a minority of cases.

Reference: Robbins and Cotran Pathologic Basis of Disease, 10th ed.

High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP

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