Which is the most common histological subtype of endometrial carcinoma?
- A Endometrioid adenocarcinoma ✓
- B Clear cell carcinoma
- C Uterine serous carcinoma
- D Mixed Mullerian tumour
Explanation
Endometrioid adenocarcinoma accounts for approximately 80 to 85 percent of endometrial carcinomas and is typically oestrogen dependent, arising against a background of hyperplasia. Uterine serous carcinoma contributes roughly 10 percent and clear cell about 4 percent, both belonging to the biologically aggressive Type II category. The key fact that eliminates the distractors is that serous and clear cell types, although high yield, together form a minority of cases.
Reference: Robbins and Cotran Pathologic Basis of Disease, 10th ed.
High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP
Written and medically reviewed by the StethoPrep medical team.