Which histological subtype accounts for the majority of endometrial carcinomas worldwide?

• A Endometrioid adenocarcinoma ✓
• B Uterine serous carcinoma
• C Clear cell carcinoma
• D Mixed Mullerian tumour

Explanation

Endometrioid adenocarcinoma constitutes roughly 80% of endometrial carcinomas. It arises in a background of hyperoestrogenism, is preceded by atypical hyperplasia or endometrial intraepithelial neoplasia, and carries a good prognosis when detected early. Uterine serous carcinoma, clear cell carcinoma, and carcinosarcoma together form the minority Type II group; they are oestrogen independent, arise in atrophic endometrium, and are far less common.

Reference: Williams Gynecology, 4th ed.

High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP

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