According to the FIGO grading system for endometrioid adenocarcinoma, Grade 1 tumour is defined by what proportion of solid, nonsquamous, nonmorular growth?

• A Less than 50%
• B Less than 10%
• C Less than 25%
• D Less than 5% ✓

Explanation

FIGO grading of endometrioid carcinoma depends on the percentage of solid nonsquamous or nonmorular growth: Grade 1 is 5% or less, Grade 2 is 6% to 50%, and Grade 3 is more than 50%. Squamous differentiation and morular metaplasia are excluded because they carry no prognostic weight. Marked nuclear atypia that is out of proportion to architectural grade raises the tumour by one grade. The 50% threshold defines Grade 3, not Grade 1.

Reference: Robbins and Cotran Pathologic Basis of Disease, 10th ed.

High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP

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