A 61-year-old postmenopausal woman presents with a single episode of vaginal bleeding. Transvaginal ultrasound shows an endometrial thickness of 3 mm and a thin, regular endometrial echo. She has no other symptoms. What is the MOST appropriate next step?
- A Endometrial biopsy
- B Reassurance and follow-up ultrasound in 6 months ✓
- C Diagnostic hysteroscopy with directed biopsy
- D CT scan of abdomen and pelvis
Explanation
In postmenopausal bleeding, an endometrial thickness below 4 mm on transvaginal sonography has a negative predictive value exceeding 99% for endometrial carcinoma, so expectant management with reassurance is appropriate when bleeding is isolated. Biopsy or hysteroscopy is reserved for thickness of 4 mm or more, persistent or recurrent bleeding, or failure to visualise the cavity. Imaging of the abdomen adds nothing when the endometrium is thin.
Reference: Berek and Novak's Gynecology, 16th ed.
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