FIGO 2023 staging of endometrial carcinoma introduced a significant change. Which histological feature now upstages a previously Stage I endometrial carcinoma to Stage II?

• A Lymphovascular space invasion (substantial LVSI) and/or endocervical stromal involvement ✓
• B Myometrial invasion >50%
• C Tumor size >4 cm
• D Positive peritoneal cytology

Explanation

FIGO 2023 revised endometrial cancer staging incorporates molecular/histological classifiers. Stage I is now subdivided (IA: non-aggressive histology, invasion <50%; IB: invasion ≥50% non-aggressive; IC: aggressive histology regardless of depth). Critically, substantial LVSI plus endocervical stromal glandular involvement (previously Stage IIA in FIGO 2009) is now Stage II. Positive peritoneal cytology was removed from staging in FIGO 2009; it is not part of current staging.

Reference: Shaw's Textbook of Gynaecology, 17th ed.

High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP

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