Obstetrics & Gynaecology · Endometrial Carcinoma

A 55-year-old woman with FIGO Stage IA Grade 1 endometrioid endometrial carcinoma (superficial myometrial invasion <50%, no LVSI) undergoes TAH-BSO. According to ESMO/ESGO/ESTRO 2021 risk stratification, she is in which risk group and what adjuvant treatment is recommended?

  • A Intermediate risk — pelvic external beam radiotherapy recommended
  • B High-intermediate risk — vaginal brachytherapy recommended
  • C Low risk — no adjuvant therapy recommended
  • D High risk — carboplatin-paclitaxel chemotherapy recommended
Correct answer: C. Low risk — no adjuvant therapy recommended

Explanation

According to ESMO/ESGO/ESTRO 2021 guidelines, Stage IA Grade 1–2 endometrioid endometrial carcinoma without LVSI is classified as LOW RISK. No adjuvant treatment is recommended for low-risk patients because the recurrence risk is <5% and the benefit of radiotherapy does not outweigh the toxicity. High-intermediate risk (Stage IB Grade 1–2 without LVSI or Stage IA Grade 3 without LVSI) warrants vaginal brachytherapy. High risk warrants chemotherapy ± radiotherapy.

Reference: Shaw's Textbook of Gynaecology, 17th ed.

High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP

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