A 62-year-old post-menopausal woman undergoes hysterectomy for endometrial cancer. Histology shows grade 2 endometrioid adenocarcinoma with 60% myometrial invasion, no lymphovascular space invasion (LVSI), cervical stroma involvement present, and negative lymph nodes. According to FIGO 2023 endometrial cancer staging, this is:
- A Stage IB
- B Stage IIIA
- C Stage II ✓
- D Stage IIIC1
Correct answer: C. Stage II
Explanation
FIGO 2023 endometrial cancer staging: Stage I = confined to uterus corpus; Stage IA = < 50% myometrial invasion; Stage IB = ≥ 50% myometrial invasion without LVSI; Stage II = cervical stromal invasion (replaces the older 'cervical glandular involvement'). This tumour invades ≥ 50% myometrium AND has cervical stroma involvement with negative nodes, making it Stage II. Stage IIIA requires adnexal or serosal involvement; Stage IIIC requires lymph node positivity.
Reference: Shaw's Textbook of Gynaecology, 17th ed.
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