In which of the following patients is expectant management of an ectopic pregnancy most appropriate?
- A Beta-hCG 850 IU/L and falling on serial testing, 2 cm unruptured adnexal mass, no cardiac activity, minimal pain ✓
- B Beta-hCG 3,400 IU/L and rising, 2.5 cm mass with fetal cardiac activity
- C Beta-hCG 2,200 IU/L plateauing over three weekly values with a 4 cm adnexal mass
- D Beta-hCG 1,800 IU/L with moderate peritoneal signs and free fluid in the pouch of Douglas
Explanation
Expectant management is reasonable only in a completely asymptomatic or minimally symptomatic woman with an unruptured ectopic under about 3 cm, no cardiac activity, and an initially low beta-hCG, generally under 1,500 IU/L, that is already declining, since many such pregnancies resolve spontaneously. Rising or plateauing levels predict persistence, cardiac activity predicts rupture risk, and peritoneal signs mandate surgery.
Reference: Williams Obstetrics, 26th ed.
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Written and medically reviewed by the StethoPrep medical team.