Which is the most common site of distant metastasis in gestational choriocarcinoma?
- A Liver
- B Brain
- C Lung ✓
- D Bone
Correct answer: C. Lung
Explanation
Choriocarcinoma spreads early by the bloodstream, and the lung is involved in about 80 percent of metastatic cases, often presenting as cough or haemoptysis. Brain and liver metastases occur far less frequently and, together with a short interval from the antecedent pregnancy, place the patient in the high-risk FIGO category. Vagina is another recognised site but is still less common than lung.
Reference: Robbins and Cotran Pathologic Basis of Disease, 10th ed.
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Written and medically reviewed by the StethoPrep medical team.