Regarding heterotopic pregnancy, which statement is correct?
- A Its incidence after assisted reproduction approaches 1 in 100 clinical pregnancies ✓
- B It occurs in approximately 1 in 30,000 spontaneous conceptions
- C Demonstration of an intrauterine sac excludes the diagnosis
- D It is managed identically to intrauterine pregnancy once confirmed
Correct answer: A. Its incidence after assisted reproduction approaches 1 in 100 clinical pregnancies
Explanation
Spontaneous heterotopic pregnancy is rare, roughly 1 in 30,000, but after embryo transfer its frequency rises dramatically to about 1 in 100 because multiple embryos and tubal transfer factors operate. This is precisely why an intrauterine sac on ultrasound does not exclude an ectopic in a conception following assisted reproduction, and both sites must be evaluated. Management requires treating the extrauterine pregnancy while preserving the intrauterine one.
Reference: Williams Obstetrics, 26th ed.
High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP
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