A 26-year-old woman, Rhesus negative, is diagnosed with a 2 cm right ampullary ectopic pregnancy that is managed expectantly. She is hemodynamically stable. Which intervention is mandatory regardless of the management strategy chosen?
- A Intramuscular anti-D immunoglobulin 300 micrograms
- B Oral methotrexate 50 mg single dose
- C Intramuscular anti-D immunoglobulin 50 micrograms ✓
- D Serum β-hCG testing every 48 hours
Correct answer: C. Intramuscular anti-D immunoglobulin 50 micrograms
Explanation
Rhesus-negative women with ectopic pregnancy, even before 12 weeks gestation, should receive anti-D immunoglobulin. The recommended dose is 50 micrograms if the pregnancy is less than 12 weeks. The 300 microgram dose is reserved for sensitized events after 12 weeks or at delivery. Methotrexate is not mandatory if expectant management is chosen, though serial β-hCG is advisable.
Reference: Williams Obstetrics, 26th ed.
High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP
Written and medically reviewed by the StethoPrep medical team.