A 32-year-old woman presents at 16 weeks with hyperemesis and bilateral adnexal masses. Ultrasound shows a snowstorm appearance in the uterus and bilateral enlarged multicystic ovaries. Serum β-hCG is 400,000 mIU/mL. What is the underlying mechanism for the ovarian findings?
- A High β-hCG stimulation of theca cells ✓
- B Metastatic spread of trophoblastic tissue
- C Autoimmune oophoritis
- D Meigs syndrome
Correct answer: A. High β-hCG stimulation of theca cells
Explanation
Bilateral theca lutein cysts result from high levels of β-hCG stimulating theca lutein hyperplasia, commonly seen with complete hydatidiform moles. Metastasis does not cause multicystic ovarian masses. Autoimmune oophoritis and Meigs syndrome are unrelated to molar pregnancies.
Reference: Williams Obstetrics, 26th ed.
High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP
Written and medically reviewed by the StethoPrep medical team.