Following evacuation of a complete hydatidiform mole, beta-hCG becomes undetectable on three consecutive weekly estimations. Recommended further surveillance in a patient with no features of high-risk disease:

• A Stop all follow-up immediately once levels are normal
• B Weekly beta-hCG for 2 years
• C Monthly beta-hCG for 6 months after normalisation ✓
• D Monthly beta-hCG for 10 years

Explanation

After three consecutive normal weekly values, relapse risk falls sharply but is not zero, so monthly beta-hCG is continued for 6 months after normalisation in low-risk disease (many centres extend to 12 months for high-risk disease). Stopping immediately misses late recurrence, and intensive weekly testing for years is unnecessary and impractical. This schedule follows standard Indian textbook practice.

Reference: Ian Donald's Practical Obstetric Problems, 8th ed.

High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP

Written and medically reviewed by the StethoPrep medical team.