Obstetrics & Gynaecology · Ectopic Pregnancy and Gestational Trophoblastic Disease

Following suction evacuation of a complete hydatidiform mole, serum β-hCG monitoring should be performed at what interval until three consecutive normal levels are obtained, followed by further monitoring?

  • A Weekly until normal, then monthly for 6 months
  • B Weekly until normal, then monthly for 12 months
  • C Every 2 weeks until normal, then monthly for 6 months
  • D Weekly until normal, then every 2 weeks for 6 months
Correct answer: A. Weekly until normal, then monthly for 6 months

Explanation

After molar evacuation, β-hCG is measured weekly until three consecutive normal levels are achieved. Thereafter, monitoring continues monthly for 6 months for complete moles (6 months of normal hCG total). Contraception is advised throughout follow-up. Partial moles are followed monthly after normalization without the 6-month extension. This protocol is essential for early detection of gestational trophoblastic neoplasia.

Reference: Williams Obstetrics, 26th ed.

High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP

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