The criteria for diagnosing post-molar gestational trophoblastic neoplasia (GTN) after complete hydatidiform mole include which of the following (FIGO 2000)?

• A β-hCG plateau (≤10% change over 2 weeks) for 3 consecutive measurements over 2 weeks
• B β-hCG rise (>10% over 2 consecutive weeks) on 3 measurements over 2 weeks
• C β-hCG plateau for 4 consecutive measurements over 3 weeks ✓
• D β-hCG not normalizing by 8 weeks after evacuation

Explanation

FIGO 2000 criteria for diagnosing GTN after complete mole include: (1) β-hCG plateau of four measurements over at least 3 weeks (days 1, 7, 14, 21); (2) β-hCG rise of ≥10% over 3 consecutive weekly measurements over 2 weeks (days 1, 7, 14); (3) histological diagnosis of choriocarcinoma; or (4) β-hCG persisting for more than 6 months after evacuation. Option C correctly describes the 4-measurement plateau criterion over 3 weeks, not 3 measurements over 2 weeks (which is the rise criterion).

Reference: Williams Obstetrics, 26th ed.

High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP

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