Which clinical scenario fulfills the FIGO 2000 criteria for diagnosis of post-molar gestational trophoblastic neoplasia without histological confirmation?
- A βhCG still detectable 4 weeks after uterine evacuation
- B Uterine size greater than dates 6 weeks after evacuation
- C βhCG plateau (less than 10% rise or fall) over 3 consecutive weekly measurements for 2 weeks ✓
- D Persistence of theca-lutein cysts beyond 3 months
Correct answer: C. βhCG plateau (less than 10% rise or fall) over 3 consecutive weekly measurements for 2 weeks
Explanation
FIGO 2000 criteria for diagnosing GTN after molar pregnancy include: (1) four weekly measurements showing plateau (±10%) over 3 weeks or more; (2) βhCG rise >10% over 3 weekly measurements over 2 weeks or more; (3) histological diagnosis of choriocarcinoma; (4) βhCG remaining elevated at 6 months. A 3-consecutive-week plateau over 2 weeks (criteria 1) is sufficient for diagnosis and treatment initiation.
Reference: Williams Obstetrics, 26th ed.
High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP
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