Obstetrics & Gynaecology · Ectopic Pregnancy and Gestational Trophoblastic Disease

According to FIGO 2000 criteria, gestational trophoblastic neoplasia (GTN) is diagnosed when a post-molar patient has a plateau in beta-hCG for how many consecutive measurements over at least how many weeks?

  • A Three values over 2 weeks (≤10% rise or fall)
  • B Three values over 3 consecutive weeks showing <10% change
  • C Two values over 4 weeks showing stable levels
  • D Four values over at least 3 weeks
Correct answer: D. Four values over at least 3 weeks

Explanation

FIGO 2000 criteria for GTN diagnosis post-molar pregnancy include: (1) four or more values of serum beta-hCG plateauing (±10%) over at least 3 weeks (days 1, 7, 14, 21); (2) a rise of ≥10% in three consecutive values over at least 2 weeks; (3) persistently elevated beta-hCG >6 months after evacuation; or (4) histological diagnosis of choriocarcinoma. The 4-value plateau over 3 weeks criterion is the most commonly tested.

Reference: Williams Obstetrics, 26th ed.

High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP

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