According to FIGO 2000 criteria, gestational trophoblastic neoplasia (GTN) is diagnosed when a post-molar patient has a plateau in beta-hCG for how many consecutive measurements over at least how many weeks?
- A Three values over 2 weeks (≤10% rise or fall)
- B Three values over 3 consecutive weeks showing <10% change
- C Two values over 4 weeks showing stable levels
- D Four values over at least 3 weeks ✓
Explanation
FIGO 2000 criteria for GTN diagnosis post-molar pregnancy include: (1) four or more values of serum beta-hCG plateauing (±10%) over at least 3 weeks (days 1, 7, 14, 21); (2) a rise of ≥10% in three consecutive values over at least 2 weeks; (3) persistently elevated beta-hCG >6 months after evacuation; or (4) histological diagnosis of choriocarcinoma. The 4-value plateau over 3 weeks criterion is the most commonly tested.
Reference: Williams Obstetrics, 26th ed.
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