A 34-year-old woman completed treatment for a hydatidiform mole 8 months ago with beta-hCG normalisation. She now presents with a lung nodule, serum beta-hCG of 4,600 mIU/mL, and no new intrauterine pregnancy. For WHO prognostic scoring (FIGO/WHO 2000 scoring system), the interval from index pregnancy is scored as 0 for <4 months, 1 for 4–6 months, 2 for 7–12 months, and 4 for >12 months. What score does the 8-month interval contribute?

• A 1
• B 4
• C 0
• D 2 ✓

Explanation

In the FIGO/WHO 2000 prognostic scoring system for gestational trophoblastic neoplasia, the interval from the index pregnancy is scored as: 0 = <4 months, 1 = 4–6 months, 2 = 7–12 months, 4 = >12 months. An 8-month interval falls in the 7–12 month range, contributing a score of 2. This system guides treatment allocation: low-risk (≤6) → single-agent methotrexate; high-risk (≥7) → multi-agent EMA-CO.

Reference: Williams Obstetrics, 26th ed.

High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP

Written and medically reviewed by the StethoPrep medical team.