A woman with severe preeclampsia at 34 weeks develops abruptio placentae and delivers a stillborn. Six hours postpartum she has oozing from the IV site and ecchymosis. Platelet count is 60,000/cu mm, fibrinogen is 120 mg/dL, and D-dimer is elevated. What is the most likely diagnosis?
- A Disseminated intravascular coagulation ✓
- B HELLP syndrome
- C Idiopathic thrombocytopenic purpura
- D Vitamin K deficiency
Correct answer: A. Disseminated intravascular coagulation
Explanation
Abruptio placentae is a classic trigger for DIC. The combination of thrombocytopenia, low fibrinogen, elevated D-dimer, and bleeding from sites confirms consumptive coagulopathy. HELLP may coexist but does not explain the low fibrinogen and elevated D-dimer. ITP and vitamin K deficiency do not fit this acute consumptive picture.
Reference: Williams Obstetrics, 26th ed.
High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP
Written and medically reviewed by the StethoPrep medical team.