A 32-year-old woman with placenta previa accreta undergoes cesarean delivery. After delivery of the baby, the placenta is left in situ and the uterus is closed. Which of the following is the most appropriate adjuvant therapy to accelerate placental resorption?

• A Tranexamic acid
• B Oxytocin infusion
• C Misoprostol
• D Methotrexate ✓

Explanation

Methotrexate is used as adjuvant therapy in conservative management of placenta accreta to promote placental resorption by inhibiting trophoblastic proliferation. However, its role is controversial and not universally recommended. Oxytocin and misoprostol are ineffective for resorption.

Reference: Williams Obstetrics, 26th ed.

High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP

Written and medically reviewed by the StethoPrep medical team.