The WOMAN trial (World Maternal Antifibrinolytic Trial) demonstrated that tranexamic acid administered within how many hours of PPH onset significantly reduces death from bleeding?
- A Within 1 hour
- B Within 3 hours ✓
- C Within 6 hours
- D Within 12 hours
Correct answer: B. Within 3 hours
Explanation
The WOMAN trial (Lancet 2017) showed that tranexamic acid given within 3 hours of delivery significantly reduced death from postpartum haemorrhage without increasing thromboembolic events. Administration beyond 3 hours was not beneficial. This finding has been incorporated into WHO guidelines recommending early use of tranexamic acid for PPH.
Reference: Williams Obstetrics, 26th ed.
High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP
Written and medically reviewed by the StethoPrep medical team.