In a pregnant woman with sickle cell disease, which of the following is the MOST common obstetric complication?
- A Gestational hypertension and pre-eclampsia
- B Preterm labour and fetal growth restriction ✓
- C Placenta previa
- D Macrosomia and shoulder dystocia
Correct answer: B. Preterm labour and fetal growth restriction
Explanation
Sickle cell disease in pregnancy is associated with increased rates of preterm labour, spontaneous abortion, and fetal growth restriction due to placental infarction from sickling in the uteroplacental circulation. Pre-eclampsia rates are also elevated but preterm birth and FGR are the most common obstetric complications. Placenta previa is not specifically increased. Macrosomia is characteristic of diabetic pregnancies. Comprehensive antenatal care with folate supplementation and pain crisis management is essential.
Reference: Williams Obstetrics, 26th ed.
High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP
Written and medically reviewed by the StethoPrep medical team.