In a pregnant woman with WHO Class IV cardiac disease (Eisenmenger syndrome), pregnancy is associated with approximately what maternal mortality rate?
- A 1–5%
- B 30–50% ✓
- C 5–15%
- D Negligible if caesarean section is performed
Correct answer: B. 30–50%
Explanation
Eisenmenger syndrome (irreversible pulmonary hypertension with reversal or bidirectional shunting through a congenital defect) is WHO Class IV — pregnancy is contraindicated. Maternal mortality is 30–50% and termination of pregnancy is recommended if the patient presents early. The mortality results from right heart failure, paradoxical embolism, and sudden death during peripartum haemodynamic shifts. No mode of delivery eliminates this risk.
Reference: Williams Obstetrics, 26th ed.
High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP
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