A pregnant woman at 24 weeks undergoes a 75 g 2-hour OGTT. Fasting plasma glucose is 88 mg/dL, 1-hour value is 175 mg/dL, and 2-hour value is 160 mg/dL. Using IADPSG/WHO 2013 criteria, what is the diagnosis?
- A Gestational diabetes mellitus based on the 2-hour value (≥153 mg/dL) ✓
- B Normal OGTT — no further action needed
- C Impaired glucose tolerance only — not GDM
- D Overt diabetes mellitus in pregnancy
Correct answer: A. Gestational diabetes mellitus based on the 2-hour value (≥153 mg/dL)
Explanation
IADPSG 2010/WHO 2013 criteria diagnose GDM if ANY single value meets or exceeds: fasting ≥92 mg/dL, 1-hour ≥180 mg/dL, or 2-hour ≥153 mg/dL. Here, fasting is 88 (below 92), 1-hour is 175 (below 180), and 2-hour is 160 (above 153 — GDM criterion met). GDM is therefore diagnosed on the 2-hour value alone. Overt diabetes in pregnancy requires fasting ≥126 mg/dL or 2-hour ≥200 mg/dL or random glucose ≥200 mg/dL.
Reference: Williams Obstetrics, 26th ed.
High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP
Written and medically reviewed by the StethoPrep medical team.