Which uterine anomaly carries the strongest association with recurrent first-trimester pregnancy loss?

• A Bicornuate uterus
• B Septate uterus ✓
• C Unicornuate uterus
• D Didelphys uterus

Explanation

The septate uterus has the poorest reproductive outcome among Mullerian anomalies because the fibrous, poorly vascularized septum impairs implantation and early placentation, and hysteroscopic septal resection improves subsequent live birth rates. Bicornuate and unicornuate uteruses are more strongly linked to second-trimester loss, malpresentation and preterm birth than to repeated early miscarriage. Didelphys uterus is rare and its losses are mostly later in gestation.

Reference: Williams Obstetrics, 26th ed.

High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP

Written and medically reviewed by the StethoPrep medical team.