Traditionally in India, second-trimester termination was carried out by extra-amniotic instillation of an agent through a Foley catheter placed into the extra-amniotic space. Which agent was classically used?
- A Hypertonic saline (20%)
- B Prostaglandin F2 alpha
- C Ethacridine lactate (Rivanol) ✓
- D Urea solution
Correct answer: C. Ethacridine lactate (Rivanol)
Explanation
Ethacridine lactate instilled extra-amniotically was the classical Indian method for midtrimester induction, producing abortion over 24 to 48 hours, often augmented with intravenous oxytocin. Hypertonic saline and urea were given by intra-amniotic instillation abroad and carry serious toxicity including maternal deaths, which distinguishes them from the extra-amniotic route described. Prostaglandins are administered vaginally or extra-amniotically as gels, not as the classic catheter infusion.
Reference: Ian Donald's Practical Obstetric Problems, 7th ed.
High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP
Written and medically reviewed by the StethoPrep medical team.