Microbiology · Zoonotic and Vector-Borne Infections (Leptospira, Rickettsia, Scrub Typhus, Bartonella)

Bartonella henselae, the causative agent of cat scratch disease, is transmitted by:

  • A Direct bite from an infected cat
  • B Tick bite (Ixodes species)
  • C Inhalation of cat dander contaminated with Bartonella
  • D Cat flea (Ctenocephalides felis) faeces inoculated via a cat scratch
Correct answer: D. Cat flea (Ctenocephalides felis) faeces inoculated via a cat scratch

Explanation

Cat scratch disease transmission involves the cat flea (Ctenocephalides felis) which deposits Bartonella henselae in its faeces on the cat's fur; when a cat scratches a human, flea faeces are inoculated into the wound. Cats themselves are reservoir hosts with high bacteraemia but remain healthy. The primary lesion is a papule or pustule at the scratch site followed by regional lymphadenopathy. Ticks transmit Bartonella quintana (trench fever via body louse), not B. henselae. PCR on lymph node aspirate or Warthin-Starry silver stain are diagnostic methods.

Reference: Ananthanarayan & Paniker's Textbook of Microbiology, 11th ed.

High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP

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