A 28-year-old woman at 16 weeks of gestation is due for travel-related vaccination. Which of the following vaccines is contraindicated in her pregnancy?
- A Tetanus-diphtheria-acellular pertussis (Tdap)
- B Inactivated influenza vaccine
- C Yellow fever 17D vaccine ✓
- D Hepatitis B recombinant vaccine
Correct answer: C. Yellow fever 17D vaccine
Explanation
Yellow fever 17D is a live attenuated vaccine, and live vaccines are avoided in pregnancy because of theoretical fetal infection risk; it should be given only if travel to an endemic zone cannot be deferred. Tdap is actively recommended in every pregnancy, preferably between 27 and 36 weeks, to transfer antipertussis antibodies to the fetus. Inactivated influenza and recombinant hepatitis B are killed or subunit preparations and are considered safe in pregnancy.
Reference: Park's Textbook of Preventive and Social Medicine, 27th ed.
High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP
Written and medically reviewed by the StethoPrep medical team.