A 19-year-old woman with a history of congenital syphilis has interstitial keratitis, sensorineural deafness and notched, barrel-shaped permanent central incisors. This classic combination is known as:

• A Hertoghe sign
• B Hutchinson triad ✓
• C Clutton joints with saber shins
• D Wimberger sign

Explanation

The Hutchinson triad consists of interstitial keratitis, eighth nerve deafness and Hutchinson peg-shaped central incisors, and is a hallmark of LATE congenital syphilis (manifestations appearing after two years of age). Hertoghe sign is thinning of the lateral eyebrows, Clutton joints refer to painless knee effusions, and Wimberger sign describes destruction of the medial proximal tibia seen in early congenital syphilis.

Reference: Nelson Textbook of Pediatrics, 22nd ed.

High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP

Written and medically reviewed by the StethoPrep medical team.