Which of the following correctly matches the non-venereal treponematosis with its causative agent and characteristic lesion?
- A Yaws: Treponema pallidum endemicum, hyperkeratotic plantar patches
- B Bejel: Treponema pallidum carateum, mucosal lesions of the mouth and nasopharynx
- C Yaws: Treponema pallidum pertenue, granulomatous skin and bone lesions ✓
- D Pinta: Treponema pallidum pertenue, dyschromic macules progressing to depigmentation
Explanation
Yaws is caused by Treponema pallidum subspecies pertenue and produces papillomatous and granulomatous lesions of skin and periosteum, including saber shins and gummatous bone involvement, in humid tropical regions. Bejel is caused by T. pallidum endemicum and affects oral mucosa, while pinta is caused by T. pallidum carateum and produces purely cutaneous dyschromic macules without tissue destruction. Each distractor swaps either the agent or the lesion between these three diseases.
Reference: Jawetz, Melnick and Adelberg's Medical Microbiology, 28th ed.
High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP
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