Microbiology · Rickettsia, Chlamydia, Mycoplasma, Spirochetes

An 8-year-old child with a history of untreated maternal syphilis presents with interstitial keratitis, sensorineural deafness, and notched, widely spaced upper central incisors. The combination of these three findings is known as:

  • A Hutchinson triad
  • B Plummer-Vinson syndrome
  • C Cogan syndrome
  • D Melkersson-Rosenthal syndrome
Correct answer: A. Hutchinson triad

Explanation

Late congenital syphilis produces the classic Hutchinson triad: interstitial keratitis, eighth nerve deafness, and Hutchinson teeth (notched, barrel-shaped, widely spaced central incisors). Other stigmata include mulberry molars, saddle nose, saber shins, and Clutton joints. Plummer-Vinson syndrome features iron deficiency anaemia with oesophageal webs, Cogan syndrome is autoimmune ocular and vestibular disease, and Melkersson-Rosenthal syndrome involves facial palsy with granulomatous cheilitis.

Reference: Nelson Textbook of Pediatrics, 22nd ed.

High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP

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