A 30-year-old man has urethral discharge. Gram stain shows no intracellular diplococci (NGNUD). NAAT on urethral swab is positive for Chlamydia trachomatis. Which serovars of C. trachomatis cause non-gonococcal urethritis?
- A Serovars D–K ✓
- B Serovars A, B, Ba, C
- C Serovars L1, L2, L3
- D Serovars B, D, E, L2
Correct answer: A. Serovars D–K
Explanation
Chlamydia trachomatis serovars D–K cause urogenital infections (non-gonococcal urethritis, cervicitis, PID, epididymitis, neonatal conjunctivitis, and pneumonia). Serovars A, B, Ba, and C cause trachoma (ocular disease leading to blindness). Serovars L1, L2, L3 cause lymphogranuloma venereum (LGV), an invasive STI with inguinal lymphadenopathy and bubo formation. NAAT is the gold-standard diagnostic method for all mucosal chlamydial infections. Treatment: azithromycin 1 g single dose or doxycycline 100 mg twice daily for 7 days.
Reference: Ananthanarayan & Paniker's Textbook of Microbiology, 11th ed.
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