A sexually active woman presents with mucopurulent cervical discharge and pelvic pain. NAAT (nucleic acid amplification test) of an endocervical swab is positive for Chlamydia trachomatis. Serovars responsible for genital tract infections and reactive arthritis (formerly Reiter's syndrome) are:

• A Serovars A, B, Ba, C
• B Serovars D–K ✓
• C Serovars L1, L2, L3
• D Serovars B and C only

Explanation

Chlamydia trachomatis serovars D–K cause genital tract infections (cervicitis, PID, epididymo-orchitis, neonatal inclusion conjunctivitis, neonatal pneumonia) and are the serovars implicated in reactive arthritis. Serovars A, B, Ba, C cause endemic trachoma (blindness). Serovars L1, L2, L3 cause lymphogranuloma venereum (LGV), characterised by painful inguinal lymphadenopathy (buboes) and invasive systemic disease. First-line treatment for chlamydial genital infections is azithromycin 1 g single dose or doxycycline 100 mg twice daily for 7 days.

Reference: Ananthanarayan & Paniker's Textbook of Microbiology, 11th ed.

High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP

Written and medically reviewed by the StethoPrep medical team.