Microbiology · Healthcare-Associated Infections and Hospital Microbiology (CLABSI, CAUTI, VAP, Sterilization Monitoring)

A urinary catheter-associated UTI (CAUTI) is suspected in a catheterised patient. Urine culture from a freshly collected catheter sample grows E. coli >10^5 CFU/mL with pyuria (>10 WBC/µL). The patient has fever and costovertebral angle tenderness. Which of the following is the most important preventive measure proven to reduce CAUTI rate in ICU settings?

  • A Silver alloy-coated urinary catheters for all ICU patients
  • B Systemic antibiotic prophylaxis during catheterisation
  • C Regular antiseptic bladder irrigation with chlorhexidine
  • D Daily reassessment and prompt removal of urinary catheter when no longer clinically indicated
Correct answer: D. Daily reassessment and prompt removal of urinary catheter when no longer clinically indicated

Explanation

The single most effective, evidence-based intervention to reduce CAUTI is daily review and early removal of indwelling urinary catheters using nurse-driven or electronic reminder protocols — every day of catheterisation adds a 3–7% risk of bacteriuria. Catheter-days reduction is the cornerstone of CAUTI prevention bundles. Silver alloy catheters have modest benefit in short-term catheterisation (≤7 days) but are costly and not recommended for routine use. Prophylactic antibiotics increase resistance without reducing symptomatic CAUTI. Bladder irrigation with antiseptics is not recommended and can cause mucosal irritation.

Reference: Ananthanarayan & Paniker's Textbook of Microbiology, 11th ed.

High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP

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