Microbiology · Gram-Negative Bacteria (E. coli, Salmonella, Shigella, Vibrio, Klebsiella)

Vibrio parahaemolyticus causes gastroenteritis associated with consumption of seafood. On TCBS (thiosulfate-citrate-bile-salts-sucrose) agar, it forms colonies that are:

  • A Yellow (sucrose fermenting)
  • B Blue-green (sucrose non-fermenting)
  • C Colorless (sucrose non-fermenting on MacConkey but TCBS not used for this species)
  • D Black-centered with metallic sheen (hydrogen sulfide production)
Correct answer: B. Blue-green (sucrose non-fermenting)

Explanation

On TCBS agar: Vibrio cholerae produces yellow colonies (sucrose fermenter); Vibrio parahaemolyticus produces blue-green colonies (sucrose non-fermenter, glucose fermenter only). TCBS is the selective differential medium of choice for all Vibrio species from stool specimens. V. parahaemolyticus is the leading cause of seafood-associated gastroenteritis worldwide, with the Kanagawa phenomenon (beta-hemolysis on Wagatsuma agar by thermostable direct hemolysin, TDH) being the virulence marker for pathogenic strains. V. vulnificus also produces blue-green colonies on TCBS and causes severe necrotizing fasciitis in immunocompromised patients after seafood consumption.

Reference: Ananthanarayan & Paniker's Textbook of Microbiology, 11th ed.

High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP

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