Microbiology · Applied Microbiology and Serology

As per Indian convention for the Standard Tube Agglutination Test (SAT) in the serodiagnosis of human brucellosis, a titre significant enough to suggest active infection is:

  • A 1:40 or above
  • B 1:80 or above
  • C 1:160 or above
  • D 1:640 or above
Correct answer: C. 1:160 or above

Explanation

In the standard tube agglutination test for brucellosis, titres of 1:160 or higher are considered diagnostic of active infection in non-endemic settings, and this is the accepted cut-off in Indian practice. Titres of 1:80 are regarded as equivocal and warrant repeat testing after two to three weeks. Low background titres such as 1:40 occur in normal populations exposed to cross-reacting organisms like Yersinia enterocolitica and Vibrio cholerae, so they cannot be taken as evidence of disease.

Reference: Ananthanarayan and Paniker Textbook of Microbiology, 11th ed.

High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP

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