Medicine · Valvular Heart Disease and Infective Endocarditis

Antibiotic prophylaxis against infective endocarditis is recommended before a dental extraction in which of the following patients?

  • A A 66-year-old woman with a bioprosthetic mitral valve replacement performed four years ago
  • B A 34-year-old man with mitral valve prolapse and mild mitral regurgitation
  • C A 70-year-old man who underwent coronary artery bypass grafting five years ago
  • D A 25-year-old woman with a transcatheter-closed secundum atrial septal defect placed eight months ago
Correct answer: A. A 66-year-old woman with a bioprosthetic mitral valve replacement performed four years ago

Explanation

Cardiac conditions for which endocarditis prophylaxis is advised before dental procedures are prosthetic cardiac valves (mechanical or bioprosthetic), a previous episode of infective endocarditis, certain unrepaired or recently repaired cyanotic congenital defects, and valve regurgitation in a cardiac transplant recipient. Mitral valve prolapse, prior bypass grafting and a successfully closed atrial septal defect beyond six months do not require prophylaxis under ACC/AHA guidance.

Reference: Braunwald's Heart Disease: A Textbook of Cardiovascular Medicine, 12th ed.

High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP

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