According to current guidelines, antibiotic prophylaxis for infective endocarditis is recommended before dental procedures involving manipulation of gingival tissue for which of the following cardiac conditions?

• A Mitral valve prolapse without regurgitation
• B Coronary artery stent placement 6 months ago
• C Isolated atrial septal defect (unrepaired)
• D Prosthetic cardiac valve ✓

Explanation

IE prophylaxis is recommended only for patients at highest risk of adverse outcomes: prosthetic valves, prior IE, unrepaired cyanotic CHD, repaired CHD with residual defects, and cardiac transplant recipients with valvulopathy. Mitral valve prolapse, isolated ASD, and coronary stents are NOT indications. The recommended regimen is amoxicillin 2 g orally (or ampicillin IV/IM) 30-60 minutes before the procedure.

Reference: Braunwald's Heart Disease, 12th ed.

High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP

Written and medically reviewed by the StethoPrep medical team.