A 38-year-old man presents with asymmetric oligoarthritis of the lower extremities, conjunctivitis, and painless oral ulcers. He had an episode of bloody diarrhea 3 weeks ago that resolved spontaneously. Which pathogen is most commonly associated with this reactive arthritis syndrome?
- A Shigella
- B Salmonella ✓
- C Campylobacter
- D Yersinia
Correct answer: B. Salmonella
Explanation
Reactive arthritis classically follows genitourinary (Chlamydia) or gastrointestinal infections. Among GI pathogens, Salmonella, Shigella, Campylobacter, and Yersinia are all recognized triggers, but Salmonella is one of the most commonly associated in clinical series. The classic triad is arthritis, conjunctivitis, and urethritis/cervicitis, though not all features need be present. The asymmetric lower-extremity pattern and recent GI infection are highly characteristic.
Reference: Harrison's Principles of Internal Medicine, 21st ed.
High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP
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