A 25-year-old woman presents with a 3-month history of low-grade fever, fatigue, asymmetric blood pressure readings in both arms (left 90/60, right 130/80), and a bruit over the left subclavian artery. She reports claudication of the left arm. ESR is 72 mm/hr. What is the most likely diagnosis?

• A Giant cell arteritis
• B Buerger disease
• C Polyarteritis nodosa
• D Takayasu arteritis ✓

Explanation

Takayasu arteritis affects women under 40 and involves the aorta and its major branches, causing limb claudication, asymmetric blood pressures, absent pulses, and bruits. Giant cell arteritis affects patients over 50 and causes headache, jaw claudication, and visual symptoms. Buerger disease involves small vessels in smokers. PAN affects medium vessels of visceral organs, not the aorta.

Reference: Harrison's Principles of Internal Medicine, 21st ed.

High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP

Written and medically reviewed by the StethoPrep medical team.