Medicine · Pulmonology (Asthma, COPD, Tuberculosis, Pneumonia, ILD, Pleural Diseases)

A 24-year-old woman with known asthma presents with acute breathlessness. On examination she cannot complete sentences, has a heart rate of 128/min, widespread wheeze, and peak expiratory flow is 35% of her predicted value. According to standard severity grading, which single feature in her assessment indicates LIFE-THREATENING rather than merely acute severe asthma?

  • A Inability to complete sentences
  • B Silent chest on auscultation
  • C Heart rate above 120/min
  • D Peak expiratory flow 35% of predicted
Correct answer: B. Silent chest on auscultation

Explanation

A silent chest means airflow is so reduced that not even wheeze can be generated, marking imminent respiratory arrest; it defines life-threatening asthma along with cyanosis, exhaustion, feeble effort, bradycardia or hypotension, and PEF below 33% predicted. Inability to speak sentences, tachycardia above 110/min, and PEF 33 to 50% predicted belong to the acute severe category, so option D does not cross the life-threatening threshold at 35%.

Reference: Harrison's Principles of Internal Medicine, 21st ed.

High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP

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